Posts Tagged “genetic fingerprinting”

Source: Times Online

A type of DNA analysis that could vastly increase the power of genetic fingerprinting has been developed by US scientists.

They have found a way of picking an individual’s DNA out of a mixed sample – even when that sample is contaminated by the DNA of up to 200 others. The method works even when the DNA of interest is only 0.1 per cent of the sample. At present, it is hard for forensic investigators to detect an individual’s DNA if it constitutes less than 10 per cent of a mixture, or if many other people’s DNA is present.

This means that it is almost impossible to identify a suspect’s DNA out of, for example, a collection of skin cells from the handrail of a public staircase. The new method could resolve this problem.

“This is a potentially revolutionary advance in the field of forensics,” said the paper’s senior author, David W. Craig, the head of the research group.

The team, from the Translational Genomics Research Institute in Phoenix, Arizona, developed a mathematical technique to determine whether the DNA of an individual was present in a mixture. They tested their method successfully on a variety of samples they had mixed.

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